Endocrine Abstracts

Autoimmune polyendocrine syndromes (APS) are rare groups of diseases with autoimmune failure of at least two endocrine glands. In general, APS1 first occurs with candidiasis. Hypoparathyroidism generally presents until 10 years of age, and adrenal insufficiency around 20 years. We aim to this report a young girl is presented with early onset APS1 first presenting with adrenal insufficiency.Mucocutaneous candidiasis on the oral mucosa, and ectodermal dyst...

Sheehan’s syndrome (SS) may be defined as development of anterior pituitary ischemic necrosis, first of which is caused by failure to meet the blood build-up required due to pituitary expansion secondary to lactotroph cell proliferation during pregnancy. Vasospasm, thrombosis and vascular compression of hypophyseal arteries have been described among the possible causes of SS. Additionally, expansion of pituitary gland, small sella, disseminated intravascular coagulation (...

Aim: Most diabetic patients suffer from vascular thrombotic complications. Alterations in platelet size are associated with atherosclerotic complications in patients with diabetes. The aim of study is to determine the relationship between mean platelet volume (MPV) and microvascular complications in type 2 diabetic patients.Materials and methods: Seventy-nine type 2 diabetic patients (mean age 51.0±10.8 years and BMI 31.0±5.5 kg/m2),...

Aim: Isolated male hypogonadotropic hypogonadism can be congenital or acquired. Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for cardiovascular disease. The aim of this study is to evaluate MPV values in untreated, normosmic, isolated, male, idiopatic hypogonadotropic hypogonadism (IHH) patients, and the relationships among MPV, low testosterone levels, metabolic syndrome, impaired fasting glucose (IFG) and cardiovascul...

Pregnancy in active acromegaly at reproductive age is very rare occurrence due to hyperprolactinemia, hypogonadism and side effects of treatment of acromegaly. Only a few reports were described in medical literature by now.We report a 31-year-old woman ongoing active acromegaly despite who received Octeatide LAR 30 mg treatment monthly for the control of GH and IGF1 excess until realized her pregnancy. A GH secreting pituitary macroadenoma (tumor size 2 ...

Lingual thyroid is an abnormal formation appearing as the result of a deficient descent during embryological development of the thyroid gland through the thyroglossal duct to its normal pretracheal location, and it is a rare embryological aberration. A 19 years old woman was admitted to with foreign-body-feeling, dysphonia, hoarseness, constipation. Examination showed a spherical, red fleshy and smooth contoured mass rat back of the tongue. Thyroid scan with technetium 99 m re...

Aim: Radioactive iodine (RAI) ablation therapy is used as part of the treatment for hyperthyroidism. Recently, low dose applied 131I treatment for hyperthyroidism has decreased the need for thyroidectomy. The aim of this study was to evaluate serum fasting glucose (FG) values in pre and post treatment RAI patients.Materials and Methods: Thirty-two patients with hyperthyroidism (mean age 56.0±14.5 years; range 24–83) treated with a si...

Introduction and objective: Recently, a lot of studies associated with high mean platelet level (MPV) in patients with hypo- and hyperthyroidism has reported in medical litherature. But it is not clear whether or not radioactive iodine treatment effect on platelet activity. It is well known that elevated platelet size is associated with its high enzymatic and metabolic activity. Aim of our preliminary study is to determine the platelet size via MPV level in hyperthyroid patien...

Objective: In this study we aim to investigate the association of osteoporosis and type 1 diabetes in 43 type 1 diabetic subjects and 41 control subjects.Subjects and methods: Bone mineral density of both groups was measured by DEXA. Age, BMI, waist/hip ratio, daily calcium consumption of both groups were determined. Twenty-four hours urinary calcium, phosphorus, deoxipyridinoline and pyridinoline were measured. Osteocalcin ALP, IGF-1, IBF-BP3. HbA1c, co...

Aim: To examine the endothelial functions of patients with Sheehan syndrome (SS) and to eveluate the effects of hormone replacement treatment except growth hormone on endothelial functions.Subjects and methods: Twenty-four patients with Sheehan syndrome (PSS) aged 40.83±6.43 yr and 25 healthy control women aged 41.13±6.51 yr (C) were included. Endothelial functions were evaluated with high resolution ultrasonography (flow mediated dilatation:FM...